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TrophAmine Formula 11

TrophAmine

1.5%

Dextrose

10%

Sterile water for injection

qs

Potassium phosphates

variable

Calcium gluconate

variable

Prepared with and without:

Cysteine HCl

40 mg/g of amino acids

Comments: The compatibility of calcium and phosphate was determined in an amino acids/dextrose admixture with and without cysteine HCl for 18 hours at 25 C followed by 30 minutes at 37 C. Visual inspection and microscopic examination were performed. Cysteine HCl lowers the pH and increases the amount of calcium and phosphate that can be added.

Adapted from:
Fitzgerald KA, MacKay MW. Calcium and phosphate solubility in neonatal parenteral nutrient solutions containing TrophAmine. Am J Hosp Pharm. 1986; 43:88-93.

TrophAmine11

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